A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name pals-22
Type gene
Species Caenorhabditis elegans
Tissue NA
Experiment Method PCR,other
Up/Down Up
Pro/Anti Anti
Funtion Description Through a forward genetic screen we found pals-22, a gene which is associated with aging and many human diseases such as Alzheimer's disease, to be a repressor of the cul-6/cullin gene and other IPR gene expression. Pals-22 mutants have increased thermoto
Regulation Gene NA
Year 2017
Pubmed ID 29103937
Title An Intracellular Pathogen Response Pathway Promotes Proteostasis in C. elegans.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA