| Name |
PAPP-A
|
| Type |
gene
|
| Species |
Mus musculus
|
| Tissue |
embryonic stem cells
|
| Experiment Method |
Cre recombinase-mediated excision
|
| Up/Down |
Down
|
| Pro/Anti |
Anti
|
| Funtion Description |
Analysis of mortality in life span quartiles indicated that the proportion of deaths of fPAPP-A/pos mice were lower than fPAPP-A/neg mice at young adult ages (P = 0.002 for 601-800 days) and higher than fPAPP-A/neg mice at older ages (P = 0.004 for >1000
|
| Regulation Gene |
NA
|
| Year |
2017
|
| Pubmed ID |
28600811
|
| Title |
Inducible knockdown of pregnancy-associated plasma protein-A gene expression in adult female mice extends life span
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|