Details
| Name | PARK2 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | never |
| Experiment Method | PCR,other |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | Loss-of-function caused by mutations in the parkin gene (PARK2) lead to early-onset familial Parkinson's disease. Parkin acts as a regulator of MT system during neuronal aging, and we endorse the hypothesis that MT dysfunction may be crucial in the pathog |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 29040870 |
| Title | Parkin absence accelerates microtubule aging in dopaminergic neurons. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |