| Name |
PARP
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
Human diploid WI-38 lung fibroblasts
|
| Experiment Method |
Western Blotting
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
The protein level of poly(ADP-ribose) polymerase (PARP) was strongly decreased in replicatively senescent fibroblasts. Quiescence of early-passage fibroblasts also slightly reduced the protein level of PARP. Apoptosis was not observed in replicatively sen
|
| Regulation Gene |
NA
|
| Year |
1997
|
| Pubmed ID |
9325154
|
| Title |
Down-regulation of Ku autoantigen, DNA-dependent protein kinase, and poly(ADP-ribose) polymerase during cellular senescence.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|