A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name PARP1
Type gene
Species Homo sapiens
Tissue NA
Experiment Method other
Up/Down NA
Pro/Anti Anti
Funtion Description oly(ADP-ribose) polymerases (PARPs) catalyze the post-translational modification of proteins with poly(ADP-ribose). Two PARP isoforms, PARP-1 and PARP-2, display catalytic activity by contact with DNA-strand breaks and are involved in DNA base-excision re
Regulation Gene NA
Year 2007
Pubmed ID 17913748
Title Poly(ADP-ribosyl)ation in mammalian ageing.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA