A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name PARP1
Type gene
Species Hamster
Tissue COM3 cells
Experiment Method PCR,Knockdown,other
Up/Down NA
Pro/Anti Anti
Funtion Description only cells transfected with PARP1 siRNA showed telomere shortening. Two independent PARP1 siRNAs produced the same effect. Furthermore, PARP1 knockdown reproduced perfectly the results with 3AB, and the effect of combination of both was identical to inhib
Regulation Gene NA
Year 2008
Pubmed ID 18835851
Title Rapid regulation of telomere length is mediated by poly(ADP-ribose) polymerase-1.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA