Details
| Name | PARP1 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | HCT116 |
| Experiment Method | other |
| Up/Down | NA |
| Pro/Anti | NA |
| Funtion Description | PAPR-1 possesses a dual role in modulating necrosis and autophagy under oxidative stress and DNA damage: on the one hand, overactivation of PARP-1 leads to ATP depletion and necrotic cell death; on the other hand, PARP-1 activation promotes autophagy via |
| Regulation Gene | NA |
| Year | 2009 |
| Pubmed ID | 19139632 |
| Title | To die or to live: the dual role of poly(ADP-ribose) polymerase-1 in autophagy and necrosis under oxidative stress and DNA damage. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |