| Name |
PATZ1
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
Human umbilical vein endothelial cells (HUVECs)
|
| Experiment Method |
RT-PCR;Western blot;realtime PCR;Immunohistochemical staining
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
We found that the level of POZ/BTB and AT-hook-containing zinc finger protein 1 (PATZ1) is downregulated during endothelial cell (EC) senescence.PATZ1 may have an important role as a transcriptional repressor in chromatin remodeling and transcription regu
|
| Regulation Gene |
NA
|
| Year |
2012
|
| Pubmed ID |
22052190
|
| Title |
POZ/BTB and AT-hook-containing zinc finger protein 1 (PATZ1) inhibits endothelial cell senescence through a p53 dependent pathway.
|
| Drug |
NA
|
| Disease |
atherosclerotic
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|