A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name PDK1
Type gene
Species Mus musculus
Tissue primary embryo fibroblasts
Experiment Method qPCR
Up/Down Down
Pro/Anti Pro
Funtion Description To learn more about the roles of PDK1, we generated mice that either lack PDK1 or possess PDK1 hypomorphic alleles, expressing only approximately 10% of the normal level of PDK1. PDK1(-/-) embryos die at embryonic day 9.5, displaying multiple abnormalitie
Regulation Gene NA
Year 2002
Pubmed ID 12110585
Title Essential role of PDK1 in regulating cell size and development in mice.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA