| Name |
PLA2R
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
human diploid fibroblasts
|
| Experiment Method |
PCR, Flow cytometry assay, Western blot, Immunofluorescence
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
We report that knockdown of the M-type receptor PLA2R (phospholipase A2 receptor) prevents the onset of replicative senescence and diminishes stress-induced senescence. Interestingly, expression of PLA2R increases during replicative senescence, and its ec
|
| Regulation Gene |
NA
|
| Year |
2008
|
| Pubmed ID |
19197340
|
| Title |
The M-type receptor PLA2R regulates senescence through the p53 pathway
|
| Drug |
N-acetylcysteine (NAC)
|
| Disease |
NA
|
| Environment Factors |
oxidation
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|