Details
| Name | PML |
| Type | gene |
| Species | Homo sapiens |
| Tissue | human diploid fibroblasts |
| Experiment Method | immunofluorescence |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | PML levels increased during both ras-induced arrest and replicative senescence, leading to a dramatic increase in the size and number of PODs. Forced PML expression was sufficient to promote premature senescence. |
| Regulation Gene | NA |
| Year | 2000 |
| Pubmed ID | 10950866 |
| Title | PML is induced by oncogenic ras and promotes premature senescence. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |