A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name PON1
Type gene
Species Homo sapiens
Tissue NA
Experiment Method PCR
Up/Down Down
Pro/Anti Anti
Funtion Description in healthy Sicilians ageing may be characterized by a low frequency of PON1 (-107)T 'risk' allele and by an high frequency of favourable genotypes such as (-107)CC, influencing PON1 activity and HDL-C levels.
Regulation Gene NA
Year 2004
Pubmed ID 15236768
Title Association between serum paraoxonase (PON1) gene promoter T(-107)C polymorphism, PON1 activity and HDL levels in healthy Sicilian octogenarians.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA