A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name POSTN
Type gene
Species Homo sapiens
Tissue Skin
Experiment Method RNA-seq, PCR, RNAi, Western blot
Up/Down Down
Pro/Anti Pro
Funtion Description A study of pyrroline-5-carboxylate reductase 1 (PYCR1) deficiency, which causes a progeroid syndrome, may not only shed light on its genetic contribution to autosomal recessive cutis laxa (ARCL) but also help elucidate the functional mechanisms associat
Regulation Gene NA
Year 2018
Pubmed ID 30574417
Title A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals POSTN As a New Element in Proline Metabolic Disorder
Drug cycloheximide (CHX)
Disease NA
Environment Factors NA
Circulating 1
Variant NA
High-throughput NA