| Name |
PPP1CA
|
| Type |
gene
|
| Species |
Mus musculus
|
| Tissue |
MEFs
|
| Experiment Method |
qRT-PCR,Northern Blot,Western Blots,other
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
PPP1CA is induced by Ras; its inactivation inhibits Ras-induced senescence, presumably by inhibiting pRb dephosphorylation. Finally, PPP1CA seems to strongly co-localize with pRb only during senescence, suggesting that PP1alpha activation during senescenc
|
| Regulation Gene |
NA
|
| Year |
2008
|
| Pubmed ID |
18800172
|
| Title |
Characterization of the p54 response to oncogene-induced senescence.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|