| Name |
PRKDC
|
| Type |
gene
|
| Species |
Mus musculus
|
| Tissue |
hESC
|
| Experiment Method |
PCR,microarray,Co-Immunoprecipitation
|
| Up/Down |
Down
|
| Pro/Anti |
Anti
|
| Funtion Description |
HGPS is a rare and fatal human premature ageing disease, characterized by premature arteriosclerosis and degeneration of vascular smooth muscle cells (SMCs). HGPS is caused by a single point mutation in the lamin A (LMNA) gene, resulting in the generation
|
| Regulation Gene |
NA
|
| Year |
2011
|
| Pubmed ID |
21368881
|
| Title |
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|