Details
| Name | PRMT5 |
| Type | gene |
| Species | Mus musculus |
| Tissue | Brain |
| Experiment Method | RT-PCR;Western blot |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | In vitro and in vivo studies revealed that among the 4 PRMT5 inhibitors, treatment of GBM cells with compound 5 (CMP5) mirrored the effects of PRMT5 knockdown wherein it led to apoptosis of differentiated GBM cells and drove undifferentiated primary patie |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 29106602 |
| Title | PRMT5 as a druggable target for glioblastoma therapy |
| Drug | CMP5 |
| Disease | glioblastoma |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |