Details
| Name | PRPF8 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | Retina |
| Experiment Method | PCR,other |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | PRPF8 (pre-mRNA processing factor 8), a core component of the spliceosome, as an essential mediator in hypoxia-induced mitophagy from an RNAi screen based on a fluorescent mitophagy reporter, mt-Keima. Aged and damaged mitochondria can be selectively degr |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 30103670 |
| Title | Autosomal dominant retinitis pigmentosa-associated gene PRPF8 is essential for hypoxia-induced mitophagy through regulation ULK1 mRNA splicing. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |