A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name PSMB5
Type gene
Species Homo sapiens
Tissue NA
Experiment Method RT-PCR
Up/Down Down
Pro/Anti Anti
Funtion Description Collectively, our work reveals a critical role of PSMB5 in 20S proteasome-mediated protection against replicative senescence, pointing to a possible strategy for maintaining the integrity of culture-expanded hBMSCs by manipulating the expression of PSMB5.
Regulation Gene NA
Year 2014
Pubmed ID 24393841
Title Ameliorating replicative senescence of human bone marrow stromal cells by PSMB5 overexpression.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA