A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name R148.3
Type gene
Species Caenorhabditis elegans
Tissue Caenorhabditis elegans
Experiment Method Quantitative real-time PCR;Pharyngeal pumping assay;Fixed Oil Red O staining;Live Nile Red staining
Up/Down Up
Pro/Anti NA
Funtion Description RNAi of R148.3 at both L1 and young-adult stages robustly diminished mean and maximal lifespan of wild-type worms, and also abolished the long-lived phenotypes of eat-2 and daf-2/InsR mutants. Based on these data, we propose that R148.3 is an SS that modu
Regulation Gene NA
Year 2017
Pubmed ID 28620088
Title The R148.3 Gene ModulatesCaenorhabditis elegansLifespan and Fat Metabolism
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA