A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Rac1
Type gene
Species Homo sapiens
Tissue human diploid fibroblasts
Experiment Method RNAi
Up/Down NA
Pro/Anti Pro
Funtion Description Moreover, the Rho GTPases Rac1 and Cdc42 were found to be highly activated in senescent cells. The active mutants of Rac1 and Cdc42 (Fig. 5D) were found to be able to induce morphological changes similar to those of senescent HDF cells.These results indic
Regulation Gene NA
Year 2004
Pubmed ID 15263006
Title Morphological adjustment of senescent cells by modulating caveolin-1 status.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant somatic mutation
High-throughput NA