Details
| Name | RAD21 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | RNAi,RT-PCR |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Importantly, we showed that knockdown of RAD21 resulted in the appearance of several senescent markers, including enhanced senescence-associated B-galactosidase activity and heterochromatin focus formation, as well as elevated p21 protein levels and RB1 p |
| Regulation Gene | NA |
| Year | 2016 |
| Pubmed ID | 26529363 |
| Title | Suppression of RAD21 Induces Senescence of MDA-MB-231 Human Breast Cancer Cells Through RB1 Pathway Activation Via c-Myc Downregulation. |
| Drug | NA |
| Disease | breast cancer |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |