Details
| Name | RB1 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | Adenovirus inactivate |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | A recent study showed that SirT1 levels are increased in lung tumour cell lines17, suggesting that oncogenic transformation may induce SirT1. As loss of pRb function and deregulation of E2F1 is part of the transformation process, E2F1 may have a role in S |
| Regulation Gene | NA |
| Year | 2006 |
| Pubmed ID | 16892051 |
| Title | Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |