A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name RB1
Type gene
Species Mus musculus
Tissue MSCs
Experiment Method In SituSenescence-Associated Beta-Galactosidase Assay;RT-PCR, and Real-Time PCR;Western Blotting
Up/Down NA
Pro/Anti NA
Funtion Description We analyzed the role of the retinoblastoma gene family in regulating senescence in mice and humans. Silencing experiments with each member of the gene family in mesenchymal stromal cells (MSCs) and fibroblasts from mouse and human tissues demonstrated tha
Regulation Gene NA
Year 2017
Pubmed ID 28865301
Title Misidentified Human Gene Functions with Mouse Models: The Case of the Retinoblastoma Gene Family in Senescence
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA