A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name RFC4
Type gene
Species Homo sapiens
Tissue blood
Experiment Method PCR,other
Up/Down Down
Pro/Anti Pro
Funtion Description The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consistin
Regulation Gene NA
Year 2018
Pubmed ID 29449545
Title Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA