| Name |
RSK4
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
colon, renal, colon adenomas
|
| Experiment Method |
PCR, Western blot
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
In vitro overexpression of RSK4 induced cell arrest and senescence features in normal fibroblasts and malignant colon carcinoma cell lines. Interestingly, in these cell lines RSK4 mRNA levels were increased both in replicative and stress-induced senescenc
|
| Regulation Gene |
NA
|
| Year |
2009
|
| Pubmed ID |
19584160
|
| Title |
Regulation of replicative and stress-induced senescence by RSK4, which is down-regulated in human tumors.
|
| Drug |
cisplatin
|
| Disease |
colon and renal carcinomas, colon cancer
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|