A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SA2
Type gene
Species Homo sapiens
Tissue COC
Experiment Method qPCR;Western blot
Up/Down Down
Pro/Anti Anti
Funtion Description SA1 and SA2 transcripts were both detected in all cumulus cells analyzed and the relative amount showed a clear decreasing trend according to the age of patients. A significant increase in SA1 and SA3 was disclosed in high responder women compared to poor
Regulation Gene NA
Year 2018
Pubmed ID 29481647
Title SA1/SA2 cohesion proteins and SIRT1- NAD+ deacetylase modulate telomere homeostasis in cumulus cells and are eligible biomarkers of ovarian aging
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA