A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Sema3a
Type gene
Species Homo sapiens
Tissue breast
Experiment Method PCR,other
Up/Down Up
Pro/Anti Pro
Funtion Description Sema3a (positively regulating bone mass) in brain was downregulated was upregulated in tibia callus after ovariectomy, zileuton could counteract these effects. Rbbp4 (involved in age-related memory loss) was increased in tibia callus after ovariectomy.
Regulation Gene NA
Year 2018
Pubmed ID 28860177
Title Effect of zileuton on osteoporotic bone and its healing, expression of bone, and brain genes in rats.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA