Details
| Name | SERPINE1 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | other |
| Up/Down | NA |
| Pro/Anti | NA |
| Funtion Description | Genes involved in cardiovascular diseases (CVD) play an opposite role in human longevity. The alpha1-antitrypsin (AAT) is a serine-protease inhibitor(SERPINE1) required for the prevention of proteolytic tissue damage, by neutrophil elastase. |
| Regulation Gene | NA |
| Year | 2007 |
| Pubmed ID | 17048073 |
| Title | Alpha1-antitrypsin heterozygosity plays a positive role in attainment of longevity. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |