A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name AKT
Type gene
Species Homo sapiens
Tissue endothelial
Experiment Method Western blotting
Up/Down Up
Pro/Anti Pro
Funtion Description Akt activity increases along with cellular senescence and that inhibition of Akt extends the lifespan of primary cultured human endothelial cells.
Regulation Gene NA
Year 2004
Pubmed ID 14713953
Title Akt negatively regulates the in vitro lifespan of human endothelial cells via a p53/p21-dependent pathway.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA