| Name |
SGF73
|
| Type |
gene
|
| Species |
Yeast
|
| Tissue |
Yeast
|
| Experiment Method |
Chromatin immunoprecipitation;ChIP-Seq analysis;anti-Flag immunoprecipitations
|
| Up/Down |
NA
|
| Pro/Anti |
Anti
|
| Funtion Description |
Deletion ofSGF73dramatically extends replicative lifespan (RLS) in yeast.These findings implicate altered ribosomal protein expression in sgf73 delta yeast RLS and highlight altered acetylation as a pathway of relevance for SCA7 neurodegeneration.
|
| Regulation Gene |
NA
|
| Year |
2017
|
| Pubmed ID |
28568901
|
| Title |
The replicative lifespan-extending deletion ofSGF73results in altered ribosomal gene expression in yeast
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
Deletion mutation
|
| High-throughput |
NA
|