Details
| Name | SIR2 |
| Type | gene |
| Species | Caenorhabditis elegans |
| Tissue | C. elegans strains |
| Experiment Method | qPCR |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | Here we report that a duplication containing sir-2.1-the C. elegans gene most homologous to yeast SIR2-confers a lifespan that is extended by up to 50%. Genetic analysis indicates that the sir-2.1 transgene functions upstream of daf-16 in the insulin-like |
| Regulation Gene | NA |
| Year | 2001 |
| Pubmed ID | 11242085 |
| Title | Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |