Details
| Name | sir-2.1 |
| Type | gene |
| Species | Caenorhabditis elegans |
| Tissue | C. elegans strains |
| Experiment Method | qPCR;qRT-PCR; |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | The longevity effect was suppressed in sir-2.1, daf-16 and skn-1-deficient worms. Killed BL induced DAF-16 nuclear localisation and increased the expression of the DAF-16 target gene hsp-12.6.These results revealed that the physiological effects of killed |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 30178731 |
| Title | Killed Bifidobacterium longum enhanced stress tolerance and prolonged life span of Caenorhabditis elegans via DAF-16. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |