A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SIRT1
Type gene
Species Mus musculus
Tissue muscle tissue
Experiment Method qPCR,Western blot
Up/Down Up
Pro/Anti Pro
Funtion Description Sirt1 inhibition reversed the protective effect of TLR9 KO on skeletal muscle composition in aged mice
Regulation Gene NA
Year 2019
Pubmed ID 31003004
Title Inhibition of TLR9 attenuates skeletal muscle fibrosis in aged sarcopenic mice via the p53/SIRT1 pathway
Drug drug
Disease Sarcopenia
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA