A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SIRT1
Type gene
Species Homo sapiens
Tissue liver
Experiment Method PCR,other
Up/Down Up
Pro/Anti Anti
Funtion Description SIRT1 regulate aging-related proteins. Studies suggest that the human SIRT1 function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative
Regulation Gene NA
Year 2018
Pubmed ID 29402742
Title Novel SIRT1 activator MHY2233 improves glucose tolerance and reduces hepatic lipid accumulation in db/db mice
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA