A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SIRT1
Type gene
Species Homo sapiens
Tissue NA
Experiment Method Knockdown by siRNA
Up/Down NA
Pro/Anti Anti
Funtion Description SirT1 inhibits p53 and forkhead transcription factors, suggesting that SirT1 is involved in regulating cell survival and stress response in mammalian organisms
Regulation Gene NA
Year 2006
Pubmed ID 16892051
Title Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage.
Drug Etoposide
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA