Details
| Name | SIRT1 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | other |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | Acetylated lysine residues of p53, MyoD, FOXO, and TAF168 are substrates for NAD-dependent histone deacetylation by human SIRT1 (hSIRT1) and murine Sir2 (mSir2), which are the closest homologs to yeast Sir2. Sir2-dependent deacetylation of p53 repressed p |
| Regulation Gene | NA |
| Year | 2006 |
| Pubmed ID | 16923962 |
| Title | Hormonal control of androgen receptor function through SIRT1. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |