Details
| Name | AKT1 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | Brain |
| Experiment Method | other |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | However, reducing the insulin-related signal in neurons activates GSK- 3B by impairing PI3 kinase/Akt activity, making neurons more vulnerable to apoptotic stimuli, and potentially leading to aging related changes in the brain. |
| Regulation Gene | NA |
| Year | 2006 |
| Pubmed ID | 16914869 |
| Title | GSK-3 is essential in the pathogenesis of Alzheimer's disease. |
| Drug | NA |
| Disease | Alzheimer's disease |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |