Details
| Name | SIRT1 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | Skin |
| Experiment Method | other |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | The class III histone deacetylase (HDAC), SIRT1, is a mammalian homologue of the Saccharomyces cerevisiae chromatin-silencing factor Sir2 that regulates longevity. SIRT1 regulates cell survival via deacetylation of p53 and forkhead transcription factors, |
| Regulation Gene | NA |
| Year | 2007 |
| Pubmed ID | 17180656 |
| Title | Strong expression of a longevity-related protein, SIRT1, in Bowen's disease. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |