| Name |
SIRT1
|
| Type |
gene
|
| Species |
Mus musculus
|
| Tissue |
MEFs
|
| Experiment Method |
RT-PCR,other
|
| Up/Down |
NA
|
| Pro/Anti |
Anti
|
| Funtion Description |
SIRT1 as a functional regulator of PGC-1alpha that induces a metabolic gene transcription program of mitochondrial fatty acid oxidation.These results have implications for understanding selective nutrient adaptation and how it might impact lifespan or met
|
| Regulation Gene |
NA
|
| Year |
2007
|
| Pubmed ID |
17347648
|
| Title |
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
low glucose concentrations
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|