Details
| Name | SIRT1 |
| Type | gene |
| Species | Dog |
| Tissue | Heart |
| Experiment Method | DNA microarray analyses |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | Sirt1 was significantly upregulated (4- to 8-fold) in response to pressure overload and oxidative stress in nontransgenic adult mouse hearts. Low (2.5-fold) to moderate (7.5-fold) overexpression of Sirt1 in transgenic mouse hearts attenuated age-dependent |
| Regulation Gene | NA |
| Year | 2007 |
| Pubmed ID | 17446436 |
| Title | Sirt1 regulates aging and resistance to oxidative stress in the heart. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |