Details
| Name | SIRT1 |
| Type | gene |
| Species | Rat Rattus |
| Tissue | cortical primary neurons |
| Experiment Method | other |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | The SIR2 gene promotes longevity in a variety of organisms and may underlie the health benefits of caloric restriction, a diet that delays aging and neurodegeneration in mammals. Here, we report that a human homologue of SIR2, SIRT1, is upregulated in mou |
| Regulation Gene | NA |
| Year | 2007 |
| Pubmed ID | 17581637 |
| Title | SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. |
| Drug | NA |
| Disease | AD,ALS |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |