Details
| Name | SIRT1 |
| Type | gene |
| Species | Mus musculus |
| Tissue | NA |
| Experiment Method | Knockin,PCR |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | Overexpression of Sir2 extends lifespan in yeast, C. elegans and Drosophila by a mechanism overlapping moderate calorie restriction (CR). In mice, CR not only engenders longevity, but also triggers two important organismal phenotypes, improved physical fu |
| Regulation Gene | NA |
| Year | 2007 |
| Pubmed ID | 17877786 |
| Title | SIRT1 transgenic mice show phenotypes resembling calorie restriction. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |