A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SIRT1
Type gene
Species Mus musculus
Tissue NA
Experiment Method PCR,Immunoblots,other
Up/Down NA
Pro/Anti Anti
Funtion Description CR did not extend lifespan of SirT1-null mice. Thus, SirT1 is an important regulator of energy metabolism and, like its orthologues from simpler eukaryotes, the SirT1 protein appears to be required for a normal response to caloric restriction.
Regulation Gene NA
Year 2008
Pubmed ID 18335035
Title SirT1 regulates energy metabolism and response to caloric restriction in mice.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA