A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SIRT1
Type gene
Species Mus musculus
Tissue MEFs
Experiment Method qRT-PCR,Southern blo,Northern blot,Western blot.other
Up/Down Up
Pro/Anti NA
Funtion Description Transgenic Sirt1 mice under a high-fat diet show lower lipid-induced inflammation along with better glucose tolerance, and are almost entirely protected from hepatic steatosis. We present data indicating that such beneficial effects of Sirt1 are due to at
Regulation Gene NA
Year 2008
Pubmed ID 18599449
Title Sirt1 protects against high-fat diet-induced metabolic damage.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA