Details
| Name | SIRT1 |
| Type | gene |
| Species | Mus musculus |
| Tissue | NA |
| Experiment Method | RT-PCR,other |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | A central focus of aging research is to determine how calorie restriction (CR) extends lifespan and delays diseases of aging. SIRT1, the mammalian ortholog of Sir2 in yeast, is a longevity factor which mediates dietary restriction in diverse species. |
| Regulation Gene | NA |
| Year | 2008 |
| Pubmed ID | 18799131 |
| Title | The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration. |
| Drug | NA |
| Disease | neurodegenerative diseases |
| Environment Factors | caloric restriction |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |