A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SIRT1
Type gene
Species Homo sapiens
Tissue NA
Experiment Method RT-PCR,other
Up/Down NA
Pro/Anti Anti
Funtion Description Heat shock factor 1 (HSF1) is essential for protecting cells from protein-damaging stress associated with misfolded proteins and regulates the insulin-signaling pathway and aging. Here, we show that human HSF1 is inducibly acetylated at a critical residue
Regulation Gene NA
Year 2009
Pubmed ID 19229036
Title Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA