| Name |
SIRT1
|
| Type |
gene
|
| Species |
Mus musculus
|
| Tissue |
Brain
|
| Experiment Method |
RT-PCR,Western blot,other
|
| Up/Down |
NA
|
| Pro/Anti |
NA
|
| Funtion Description |
Mammalian life span can be extended by both calorie restriction (CR) and mutations that diminish somatotropic signaling. Sirt1 is a mediator of many effects of CR in mammals.
|
| Regulation Gene |
NA
|
| Year |
2009
|
| Pubmed ID |
20008932
|
| Title |
Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|