| Name |
SIRT1
|
| Type |
gene
|
| Species |
Mus musculus
|
| Tissue |
MEFs
|
| Experiment Method |
PCR,Immunofluorescence,FISH,ChIP
|
| Up/Down |
NA
|
| Pro/Anti |
Anti
|
| Funtion Description |
A mouse model of SIRT1 (super) was obtained by studying loss of function (SIRT1 deficiency) and function. Results indicate that SIRT1 is a positive regulator of telomere length in vivo and attenuates telomere shortening associated with aging, an effect de
|
| Regulation Gene |
NA
|
| Year |
2010
|
| Pubmed ID |
21187328
|
| Title |
SIRT1 contributes to telomere maintenance and augments global homologous recombination.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|