Details
| Name | SIRT1 |
| Type | gene |
| Species | Mus musculus |
| Tissue | NA |
| Experiment Method | other |
| Up/Down | Up |
| Pro/Anti | NA |
| Funtion Description | we demonstrate that brain-specific Sirt1-overexpressing (BRASTO) transgenic mice show significant life span extension in both males and females, and aged BRASTO mice exhibit phenotypes consistent with a delay in aging. These phenotypes are mediated by enh |
| Regulation Gene | NA |
| Year | 2013 |
| Pubmed ID | 24011076 |
| Title | Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |