A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SIRT1
Type gene
Species Mus musculus
Tissue embryonic
Experiment Method Western
Up/Down Down
Pro/Anti Anti
Funtion Description Extended replicative life span of SIRT1-deficient MEFs correlates with enhanced proliferative capacity under conditions of chronic, sublethal oxidative stress.
Regulation Gene NA
Year 2005
Pubmed ID 16054100
Title Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA